***Meeting program subject to change.
Available Formats: = Livestream
= In Person
= On Demand
4:00–8:00 PM
British/Columbia Foyer
6:00–8:00 PM
British/Columbia Foyer
7:30–8:30 AM
Vancouver Island Room
Welcome and Keynote Session
8:30–10:00 AM
Columbia Ballroom
Linda G. Griffith, Massachusetts Institute of Technology
Humanizing Drug Discovery: Microphysiological Systems to Model MASH
Rohit Loomba, University of California, San Diego, Salk Institute
Translational Update on MASH
10:00–10:20 AM
British/Columbia Foyer
Mechanisms of Hepatocyte Metabolic Dysfunction in Obesity
10:20–11:45 AM
Columbia Ballroom
Rotonya Carr, University of Washington
Unraveling the Role of Lipid Droplet Proteins in MASLD
Mark A Herman, Baylor College of Medicine
Carbohydrate Metabolism and Steatosis, Intersection of Hepatokines and Metabolism
Jennifer L. Estall, Institut de Recherches Cliniques de Montréal
Understanding the Fasting Response in Hepatic Lipid Metabolism
Short Talk(s) Chosen from Abstracts
11:45–1:00 PM
British/Columbia Ballroom
1:00–10:00 PM
British/Columbia Ballroom
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Columbia Ballroom
Short Talks Chosen from Abstracts
4:30–5:00 PM
British/Columbia Foyer
Endocrine Regulators of Hepatocyte Metabolic Functions
5:00–7:00 PM
Columbia Ballroom
Magdalene K. Montgomery, University of Melbourne
Using Genome-Wide CRISPR Screens to Identify Novel Regulators of Hepatic Lipid Metabolism in MASH
Kristina Schoonjans, École Polytechnique Fédérale de Lausanne – EPFL
Gut-Liver Axis
Timothy P. Rolph, Akero Therapeutics
FGFs in MASH Pathogenesis and Therapy
Filip K. Knop, Gentofte Hospital, University of Copenhagen
Role of Glucagon and Incretins in MASH
Short Talk(s) Chosen from Abstracts
7:00–8:00 PM
Vancouver Island Room
7:30–10:00 PM
British/Columbia Ballroom
7:30–8:30 AM
Vancouver Island Room
8:00–8:30 AM
British/Columbia Ballroom
8:15–5:00 PM
British/Columbia Ballroom
Intercellular and Interorgan Crosstalk in Development of Liver Disease
8:30–11:30 AM
Columbia Ballroom
Xingxing Kong, Fudan University
Adipose-Muscle-Liver Crosstalk
Ruchi Bansal, University of Twente
Single-Cell Phenomics and EV-Omics to Unravel Cellular and Organ Crosstalk in MASH and Liver Cancer
Ornella Barrandon, Cellarity
Revealing Novel MASH Biology at Single Cell Resolution
Short Talk(s) Chosen from Abstracts
9:30–9:50 AM
British/Columbia Foyer
11:30–12:30 PM
Vancouver Island Room
12:00–2:30 PM
British/Columbia Ballroom
3:00–4:30 PM
British Ballroom
4:30–5:00 PM
British/Columbia Foyer
Intrahepatic Determinants of Liver Inflammation and Fibrosis in MASH
5:00–7:00 PM
Columbia Ballroom
Utpal B. Pajvani, Columbia University Medical Center
Adipogenic Reprogramming of Hepatocytes as a Contributor to Fibrosis
Mathias Florian Heikenwälder, German Cancer Research Center, DKFZ
Fueling MASH: Metabolic Drivers and Inflammatory Crosstalk
Ariel E. Feldstein, University of California, San Diego & Novo Nordisk
Novel Drivers of the Inflammatory Response in Liver Injury and Fibrosis
Short Talk(s) Chosen from Abstracts
7:30–8:30 AM
Vancouver Island Room
Mechanisms of Liver Regeneration and Progression to HCC
8:30–11:30 AM
Columbia Ballroom
Hao Zhu, University of Texas Southwestern Medical Center
Somatic Mutations in MASH Progression
Robert F. Schwabe, Columbia University
Regulation of Hepatocyte Metabolism by Hepatic Stellate Cells in MASH: Looking Beyond Fibrogenesis
KyeongJin Kim, Inha University
Mechanisms of MASH-Induced HCC
Short Talk(s) Chosen from Abstracts
9:30–9:50 AM
British/Columbia Foyer
Panel: Perspectives: Personalized Medicine and Patient-Centered Strategies (joint)
1:00–2:00 PM
Columbia Ballroom
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Columbia Ballroom
Short Talks Chosen from Abstracts
4:30–5:00 PM
British/Columbia Foyer
Emerging Translational Approaches to MASH
5:00–6:45 PM
Columbia Ballroom
Simon J Cockell, University of Newcastle upon Tyne
Proteo-Transcriptomic Profiles in MASLD
Diana Julie Leeming, Nordic Bioscience
Circulating Markers of Extracellular Matrix for MASLD Risk Stratification and Prediction of Response to Therapy
Katy Wack, PathAI
Bringing Precision to Pathologic Assessment for MASH: Clinical Validation of an AI-based Drug Development Tool
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Columbia Ballroom
7:00–8:00 PM
Vancouver Island Room
