***Meeting program subject to change.
Available Formats: = Livestream
= In Person
= On Demand
4:00–8:00 PM
Van Horne Foyer
6:00–8:00 PM
Van Horne Foyer
7:00–8:00 AM
President's Hall
Welcome and Keynote Address
8:00–9:00 AM
Van Horne A
Transformation of Drug Discovery and Induced Proximity through AI/ML
9:00–11:15 AM
Van Horne A
Ning Zheng, University of Washington
AI Accelerated Virtual Screening for Novel Ligands
Short Talk(s) Chosen from Abstracts
9:30–9:50 AM
Van Horne Foyer
11:15–1:00 PM
Van Horne C
1:00–10:00 PM
Van Horne C
Symposia Spotlight: Emerging Technologies and Approaches in Proximity Induction
2:30–4:30 PM
Van Horne A
4:30–5:00 PM
Van Horne Foyer
Novel Induced Proximity based Approaches
5:00–7:00 PM
Van Horne A
Amit Choudhary, Harvard Medical School
Proximity-Inducing Molecules for Protein Editing
Gerald R. Crabtree, Stanford University
Transcriptional Chemical Inducers of Proximity
Elena De Vita, Queen Mary University of London
Targeted Protein Dephosphorylation vial PHOSTACs
Short Talk(s) Chosen from Abstracts
7:00–8:00 PM
President's Hall
7:30–10:00 PM
Van Horne C
7:00–8:00 AM
President's Hall
Leveraging Novel Protein Degradation Machinery for Next Generation Protein Degraders
8:00–11:00 AM
Van Horne A
Cheryl Arrowsmith, University of Toronto
Increasing the Repertoire of Chemically Recruitable E3 Ligases for Targeted Protein Degradation
Asad Taherbhoy, Foghorn Therapeutics
Novel Strategies of Targeting the Transcriptional Machinery for Degradation
Gwenn Hansen, Nurix Therapeutics
Enabling Novel Ligases for Targeted Protein Degradation through DEL based Approaches
Daniel K Nomura, University of California, Berkeley
Enabling Novel Ligases
Short Talk(s) Chosen from Abstracts
9:00–9:20 AM
Van Horne Foyer
11:00–1:00 PM
Van Horne C
1:00–10:00 PM
Van Horne C
4:30–5:00 PM
Van Horne Foyer
Induced Proximity to Modulate Protein Complexes
5:00–7:00 PM
Van Horne A
Katherine Kayser-Bricker, Halda Therapeutics
Regulated Induced Proximity Targeting Chimeras (RIPTACs)
Michelle R. Arkin, University of California, San Francisco
Utilization of Stabilizers of Protein-Protein Interactions
Jian Jin, Icahn School of Medicine at Mount Sinai
New Approaches to Target Undruggable Proteins
Short Talk(s) Chosen from Abstracts
7:00–8:00 PM
President's Hall
7:30–10:00 PM
Van Horne C
7:00–8:00 AM
President's Hall
Clinical Progress in Induced Proximity Approaches
8:00–11:00 AM
Van Horne A
Neil Bence, Bristol Myers Squibb
BMS Protein Degrader from Discovery to Clinical Development
Paula O’Connor †, Nurix Therapeutics
Advancing Novel Degraders to the Clinic (BTK and Beyond)
Short Talk(s) Chosen from Abstracts
9:00–9:20 AM
Van Horne Foyer
Panel Discussion: Driving Innovation: From Concept to Company, how to Start a Company around a New Idea
2:30–4:30 PM
Van Horne A
4:30–5:00 PM
Van Horne Foyer
Enabling Discovery and Development of Novel Induced Proximity Molecules and Glues
5:00–6:45 PM
Van Horne A
Georg E. Winter, CeMM Research Center for Molecular Medicine
Novel Glue Discovery via Isogenic Morphological Profiling
Alessio Ciulli, University of Dundee, School of Life Sciences
Expanding the Target Space of Protein Degraders
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions
6:45–7:00 PM
Van Horne A
7:00–8:00 PM
President's Hall
